A number of treatments are currently available for wet AMD. These treatments generally work by stopping the growth of new blood vessels. This means the treatments generally need to be given quickly once the blood vessels start to grow in your eye. If the blood vessels are left to grow for too long they may scar the retina and cause irreversible damage.
Unfortunately, there is currently no treatment for dry AMD. This is due to the fact that dry AMD doesn’t involve new blood vessels growing.
Treatments for wet AMD
Anti-VEGF treatment
The newest treatment available on the NHS for wet AMD is an anti-vascular endothelial growth factor (anti-VEGF) drug. As new blood vessels develop in your eye, your body creates a chemical that stimulates further new blood vessel growth. Anti-VEGF drugs work against these chemicals and stop the vessels from growing. By stopping this growth further damage to your sight is prevented.
The medicine used must be injected into the vitreous (the gel-like substance inside your eye). This is known as an intravitreal injection.
Prior to the injection, you will be given anaesthetic eye drops to numb the pain, an antibiotic drop to help prevent infection and another drop to dilate your pupil.
The injection should not be painful however your eye may be a little sore after the anaesthetic wears off.
The sight in the treated eye may be blurry because of the drop used to dilate your pupil, this should, however, wear off after a day. Some patients find that they have minor swirls in their vision in the days following the injection. Your eyes may water a bit after the injection and become red or irritated however this will improve after a few days.
If your eye becomes very painful, red or you notice that your vision is actually getting worse you should contact your hospital immediately to let them know.
Generally, you will need to receive more than one injection of anti-VEGF medication. Normally a course of three monthly injections is given initially and then you need to be monitored every four to eight weeks depending on what particular drug was given to check how well the treatment is working. Your ophthalmologist will advise you on how often you need to get your eyes tested. Many people require more injections than the initial three.
Usually, anti-VEGF treatments have a very high success rate and in the majority of people, symptoms stop getting worse. Around 25-30% of people report an improvement in their vision as a result of the treatment.
Photodynamic therapy
Anti-VEGF treatments are normally the first treatments offered to people with wet AMD. However, sometimes it is necessary to try a different treatment known as Photodynamic therapy or PDT. This is a form of laser treatment that uses a light-sensitive drug and a low energy (cold) laser to stop new blood vessels from growing.
You will receive an injection, usually in the arm, of a light-sensitive drug known as Verteporfin (Visudyne). Once this drug has travelled to the new blood vessels which grow in wet AMD, your ophthalmologist can target an extremely bright light (a cold laser) onto these blood vessels. The laser causes the drug to react which seals off any new blood vessels that may be growing.
This treatment also has to be carried out at the early stages of the blood vessel growth to ensure that the new blood vessel growth is not causing damage.
Treating dry AMD
Although there is currently no proven treatment for dry AMD some evidence suggests that high doses of vitamin A, C and E and the minerals zinc and copper when taken together may help to slow the progression of dry AMD.
A number of over the counter vitamin products are available that have been specifically designed for people with dry AMD. There is, however, no evidence that taking these vitamins will stop you from developing AMD in the first place.